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microRNA-15b-5p encapsulated by M2 macrophage-derived extracellular vesicles promotes gastric cancer metastasis by targeting BRMS1 and suppressing DAPK1 transcription

BACKGROUND: Extracellular vesicles (EVs) derived from tumor-associated macrophages are implicated in the progression and metastasis of gastric cancer (GC) via the transfer of molecular cargo RNAs. We aimed to decipher the impact of microRNA (miR)-15b-5p transferred by M2 macrophage-derived EVs in th...

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Detalles Bibliográficos
Autores principales: Cao, Yi, Tu, Yi, Xiong, Jianbo, Tan, Shengxing, Luo, Lianghua, Wu, Ahao, Shu, Xufeng, Jie, Zhigang, Li, Zhengrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027839/
https://www.ncbi.nlm.nih.gov/pubmed/35449111
http://dx.doi.org/10.1186/s13046-022-02356-8