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Blood Plasma Exosomes Contain Circulating DNA in Their Crown

It is known that circulating DNA (cirDNA) is protected from nuclease activity by proteins that form macromolecular complexes with DNA. In addition, it was previously shown that cirDNA can bind to the outer surface of exosomes. NTA analysis and real-time PCR show that exosomes from healthy females (H...

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Detalles Bibliográficos
Autores principales: Tutanov, Oleg, Shtam, Tatiana, Grigor’eva, Alina, Tupikin, Alexey, Tsentalovich, Yuri, Tamkovich, Svetlana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027845/
https://www.ncbi.nlm.nih.gov/pubmed/35453902
http://dx.doi.org/10.3390/diagnostics12040854