Targeting the NRF2/HO-1 Antioxidant Pathway in FLT3-ITD-Positive AML Enhances Therapy Efficacy

Acute myeloid leukemia (AML) is a molecularly heterogenous hematological malignancy, with one of the most common mutations being internal tandem duplication (ITD) of the juxtamembrane domain of the fms-like tyrosine kinase receptor-3 (FLT3). Despite the development of FLT3-directed tyrosine kinase i...

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Detalles Bibliográficos
Autores principales: Kannan, Sankaranarayan, Irwin, Mary E., Herbrich, Shelley M., Cheng, Tiewei, Patterson, LaNisha L., Aitken, Marisa J. L., Bhalla, Kapil, You, M. James, Konopleva, Marina, Zweidler-McKay, Patrick A., Chandra, Joya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027903/
https://www.ncbi.nlm.nih.gov/pubmed/35453402
http://dx.doi.org/10.3390/antiox11040717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027903/
https://www.ncbi.nlm.nih.gov/pubmed/35453402
http://dx.doi.org/10.3390/antiox11040717

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