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Bayesian adaptive design for pediatric clinical trials incorporating a community of prior beliefs

BACKGROUND: Pediatric population presents several barriers for clinical trial design and analysis, including ethical constraints on the sample size and slow accrual rate. Bayesian adaptive design methods could be considered to address these challenges in pediatric clinical trials. METHODS: We develo...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Travis, James, Gajewski, Byron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027907/
https://www.ncbi.nlm.nih.gov/pubmed/35448963
http://dx.doi.org/10.1186/s12874-022-01569-x