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Bayesian adaptive design for pediatric clinical trials incorporating a community of prior beliefs
BACKGROUND: Pediatric population presents several barriers for clinical trial design and analysis, including ethical constraints on the sample size and slow accrual rate. Bayesian adaptive design methods could be considered to address these challenges in pediatric clinical trials. METHODS: We develo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027907/ https://www.ncbi.nlm.nih.gov/pubmed/35448963 http://dx.doi.org/10.1186/s12874-022-01569-x |