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Retinal Circular RNA hsa_circ_0087207 Expression Promotes Apoptotic Cell Death in Induced Pluripotent Stem Cell-Derived Leber’s Hereditary Optic Neuropathy-like Models

Backgrounds: Leber’s hereditary optic neuropathy (LHON) is known as an inherited retinal disorder characterized by the bilateral central vision loss and degeneration of retinal ganglion cells (RGCs). Unaffected LHON carriers are generally asymptomatic, suggesting that certain factors may contribute...

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Detalles Bibliográficos
Autores principales: Yang, Yi-Ping, Chang, Yuh-Lih, Lai, Yun-Hsien, Tsai, Ping-Hsing, Hsiao, Yu-Jer, Nguyen, Long Hoang, Lim, Xue-Zhen, Weng, Chang-Chi, Ko, Yu-Ling, Yang, Chang-Hao, Hwang, De-Kuang, Chen, Shih-Jen, Chiou, Shih-Hwa, Chiou, Guang-Yuh, Wang, An-Guor, Chien, Yueh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027941/
https://www.ncbi.nlm.nih.gov/pubmed/35453537
http://dx.doi.org/10.3390/biomedicines10040788