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Interspecies Comparisons of the Effects of Potential Antiviral 3-Amidinophenylalanine Derivatives on Cytochrome P450 1A2 Isoenzyme

In vitro models of animals vulnerable to SARS-CoV-2 infection can support the characterization of effective antiviral drugs, such as synthetic inhibitors of the transmembrane protease serine 2 (TMPRSS2). Changes in cytochrome P450 (CYP) 1A2 activities in the presence of the potential TMPRSS2/matript...

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Detalles Bibliográficos
Autores principales: Fedor, Zsófia, Szentkirályi-Tóth, Anna, Nagy, Gábor, Szimrók, Zoltán, Varga, Eszter, Pászti, Anna, Pászti, Zoltán, Jerzsele, Ákos, Pilgram, Oliver, Steinmetzer, Torsten, Mátis, Gábor, Neogrády, Zsuzsanna, Pászti-Gere, Erzsébet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027957/
https://www.ncbi.nlm.nih.gov/pubmed/35448654
http://dx.doi.org/10.3390/vetsci9040156