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Interleukin-10 Mitigates Doxorubicin-Induced Endoplasmic Reticulum Stress as Well as Cardiomyopathy

The use of doxorubicin (Dox) in cancer patients carries the risk of cardiotoxicity via an increase in oxidative stress, mitochondrial dysfunction, and disturbed endoplasmic reticulum (ER) homeostasis in cardiomyocytes. The present study explores which of the ER transmembrane sensors is involved in D...

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Detalles Bibliográficos
Autores principales: Malik, Akshi, Bagchi, Ashim K., Jassal, Davinder S., Singal, Pawan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027958/
https://www.ncbi.nlm.nih.gov/pubmed/35453640
http://dx.doi.org/10.3390/biomedicines10040890