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AcidoCEST-UTE MRI Reveals an Acidic Microenvironment in Knee Osteoarthritis

A relationship between an acidic pH in the joints, osteoarthritis (OA), and pain has been previously demonstrated. Acidosis Chemical Exchange Saturation Transfer (acidoCEST) indirectly measures the extracellular pH through the assessment of the exchange of protons between amide groups on iodinated c...

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Detalles Bibliográficos
Autores principales: Lombardi, Alecio F., Ma, Yajun, Jang, Hyungseok, Jerban, Saeed, Tang, Qingbo, Searleman, Adam C., Meyer, Robert Scott, Du, Jiang, Chang, Eric Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027981/
https://www.ncbi.nlm.nih.gov/pubmed/35457284
http://dx.doi.org/10.3390/ijms23084466