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The Influence of Heterochronic Non-Myeloablative Bone Marrow Transplantation on the Immune System, Frailty, General Health, and Longevity of Aged Murine Recipients

The stem cell theory of aging postulates that stem cells become inefficient at maintaining the original functions of the tissues. We, therefore, hypothesized that transplanting young bone marrow (BM) to old recipients would lead to rejuvenating effects on immunity, followed by improved general healt...

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Detalles Bibliográficos
Autores principales: Jazbec, Katerina, Jež, Mojca, Švajger, Urban, Smrekar, Boštjan, Miceska, Simona, Rajčevič, Uroš, Justin, Mojca, Završnik, Janja, Malovrh, Tadej, Švara, Tanja, Gombač, Mitja, Ramšak, Živa, Rožman, Primož
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028083/
https://www.ncbi.nlm.nih.gov/pubmed/35454183
http://dx.doi.org/10.3390/biom12040595