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Regulatory Crosstalk between Physiological Low O(2) Concentration and Notch Pathway in Early Erythropoiesis
Physiological low oxygen (O(2)) concentration (<5%) favors erythroid development ex vivo. It is known that low O(2) concentration, via the stabilization of hypoxia-induced transcription factors (HIFs), intervenes with Notch signaling in the control of cell fate. In addition, Notch activation is i...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028139/ https://www.ncbi.nlm.nih.gov/pubmed/35454129 http://dx.doi.org/10.3390/biom12040540 |