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Regulatory Crosstalk between Physiological Low O(2) Concentration and Notch Pathway in Early Erythropoiesis

Physiological low oxygen (O(2)) concentration (<5%) favors erythroid development ex vivo. It is known that low O(2) concentration, via the stabilization of hypoxia-induced transcription factors (HIFs), intervenes with Notch signaling in the control of cell fate. In addition, Notch activation is i...

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Detalles Bibliográficos
Autores principales: Labat, Véronique, Bayard, Eva Nguyen van Thanh dit, Refeyton, Alice, Huart, Mathilde, Avalon, Maryse, Debeissat, Christelle, Rodriguez, Laura, de la Grange, Philippe Brunet, Ivanovic, Zoran, Vlaski-Lafarge, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028139/
https://www.ncbi.nlm.nih.gov/pubmed/35454129
http://dx.doi.org/10.3390/biom12040540