NLRP3 Inhibition Reduces rt-PA Induced Endothelial Dysfunction under Ischemic Conditions

Thrombolysis with recombinant tissue plasminogen activator (rt-PA) is a mainstay of acute ischemic stroke treatment but is associated with bleeding complications, especially after prolonged large vessel occlusion. Recently, inhibition of the NLRP3 inflammasome led to preserved blood–brain barrier (B...

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Detalles Bibliográficos
Autores principales: Bellut, Maximilian, Raimondi, Anthony T., Haarmann, Axel, Zimmermann, Lena, Stoll, Guido, Schuhmann, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028140/
https://www.ncbi.nlm.nih.gov/pubmed/35453512
http://dx.doi.org/10.3390/biomedicines10040762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028140/
https://www.ncbi.nlm.nih.gov/pubmed/35453512
http://dx.doi.org/10.3390/biomedicines10040762

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