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NLRP3 Inhibition Reduces rt-PA Induced Endothelial Dysfunction under Ischemic Conditions

Thrombolysis with recombinant tissue plasminogen activator (rt-PA) is a mainstay of acute ischemic stroke treatment but is associated with bleeding complications, especially after prolonged large vessel occlusion. Recently, inhibition of the NLRP3 inflammasome led to preserved blood–brain barrier (B...

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Detalles Bibliográficos
Autores principales:	Bellut, Maximilian, Raimondi, Anthony T., Haarmann, Axel, Zimmermann, Lena, Stoll, Guido, Schuhmann, Michael K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028140/ https://www.ncbi.nlm.nih.gov/pubmed/35453512 http://dx.doi.org/10.3390/biomedicines10040762

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