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Fluorine-Containing Drug Administration in Rats Results in Fluorination of Selected Proteins in Liver and Brain Tissue

In many pharmaceuticals, a hydrogen atom or hydroxyl group is replaced by a fluorine to increase bioavailability and biostability. The fate of fluorine released from fluorine-containing drugs is not well investigated. The aim of this study was to examine possible fluorination of proteins in rat live...

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Detalles Bibliográficos
Autores principales: Gawor, Andrzej, Gajewski, Zdzislaw, Paczek, Leszek, Czarkowska-Paczek, Bozena, Konopka, Anna, Wryk, Grzegorz, Bulska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028303/
https://www.ncbi.nlm.nih.gov/pubmed/35457021
http://dx.doi.org/10.3390/ijms23084202