Somatic Mutations of Hematopoietic Cells Are an Additional Mechanism of Body Aging, Conducive to Comorbidity and Increasing Chronification of Inflammation

It is known that the development of foci of chronic inflammation usually accompanies body aging. In these foci, senescent cells appear with a pro-inflammatory phenotype that helps maintain inflammation. Their removal with the help of senolytics significantly improves the general condition of the bod...

Descripción completa

Detalles Bibliográficos
Autores principales: Yegorov, Yegor E., Poznyak, Anastasia V., Bezsonov, Evgeny E., Zhuravlev, Alexander D., Nikiforov, Nikita G., Vishnyakova, Khava S., Orekhov, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028317/
https://www.ncbi.nlm.nih.gov/pubmed/35453534
http://dx.doi.org/10.3390/biomedicines10040782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028317/
https://www.ncbi.nlm.nih.gov/pubmed/35453534
http://dx.doi.org/10.3390/biomedicines10040782

Ejemplares similares