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Somatic Mutations of Hematopoietic Cells Are an Additional Mechanism of Body Aging, Conducive to Comorbidity and Increasing Chronification of Inflammation
It is known that the development of foci of chronic inflammation usually accompanies body aging. In these foci, senescent cells appear with a pro-inflammatory phenotype that helps maintain inflammation. Their removal with the help of senolytics significantly improves the general condition of the bod...
Autores principales: | Yegorov, Yegor E., Poznyak, Anastasia V., Bezsonov, Evgeny E., Zhuravlev, Alexander D., Nikiforov, Nikita G., Vishnyakova, Khava S., Orekhov, Alexander N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028317/ https://www.ncbi.nlm.nih.gov/pubmed/35453534 http://dx.doi.org/10.3390/biomedicines10040782 |
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