A Monoclonal Anti-HMGB1 Antibody Attenuates Neurodegeneration in an Experimental Animal Model of Glaucoma

Neuroinflammation is a crucial process for the loss of retinal ganglion cells (RGC), a major characteristic of glaucoma. High expression of high-mobility group box protein 1 (HMGB1) plays a detrimental role in inflammatory processes and is elevated in the retinas of glaucoma patients. Therefore, thi...

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Detalles Bibliográficos
Autores principales: Tonner, Henrik, Hunn, Selina, Auler, Nadine, Schmelter, Carsten, Beutgen, Vanessa M., von Pein, Harald D., Pfeiffer, Norbert, Grus, Franz H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028318/
https://www.ncbi.nlm.nih.gov/pubmed/35456925
http://dx.doi.org/10.3390/ijms23084107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028318/
https://www.ncbi.nlm.nih.gov/pubmed/35456925
http://dx.doi.org/10.3390/ijms23084107

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