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A Monoclonal Anti-HMGB1 Antibody Attenuates Neurodegeneration in an Experimental Animal Model of Glaucoma
Neuroinflammation is a crucial process for the loss of retinal ganglion cells (RGC), a major characteristic of glaucoma. High expression of high-mobility group box protein 1 (HMGB1) plays a detrimental role in inflammatory processes and is elevated in the retinas of glaucoma patients. Therefore, thi...
Autores principales: | Tonner, Henrik, Hunn, Selina, Auler, Nadine, Schmelter, Carsten, Beutgen, Vanessa M., von Pein, Harald D., Pfeiffer, Norbert, Grus, Franz H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028318/ https://www.ncbi.nlm.nih.gov/pubmed/35456925 http://dx.doi.org/10.3390/ijms23084107 |
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