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How Pyroptosis Contributes to Inflammation and Fibroblast-Macrophage Cross-Talk in Rheumatoid Arthritis

About thirty years ago, a new form of pro-inflammatory lytic cell death was observed and termed pyroptosis. Only in 2015, gasdermins were defined as molecules that create pores at the plasma membrane and drive pyroptosis. Today, we know that gasdermin-mediated death is an important antimicrobial def...

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Detalles Bibliográficos
Autores principales: Demarco, Benjamin, Danielli, Sara, Fischer, Fabian A., Bezbradica, Jelena S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028325/
https://www.ncbi.nlm.nih.gov/pubmed/35455985
http://dx.doi.org/10.3390/cells11081307