Preparation and Characterization of a Novel Mucoadhesive Carvedilol Nanosponge: A Promising Platform for Buccal Anti-Hypertensive Delivery

Carvedilol (CRV) is a non-selective third generation beta-blocker used to treat hypertension, congestive heart failure and angina pectoris. Oral administration of CRV showed poor bioavailability (25%), which might be ascribed to its extensive first-pass metabolism. Buccal delivery is known to boost...

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Detalles Bibliográficos
Autores principales: Khafagy, El-Sayed, Abu Lila, Amr S., Sallam, Nahed Mohamed, Sanad, Rania Abdel-Basset, Ahmed, Mahgoub Mohamed, Ghorab, Mamdouh Mostafa, Alotaibi, Hadil Faris, Alalaiwe, Ahmed, Aldawsari, Mohammed F., Alshahrani, Saad M., Alshetaili, Abdullah, Almutairy, Bjad K., Al Saqr, Ahmed, Gad, Shadeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028337/
https://www.ncbi.nlm.nih.gov/pubmed/35448136
http://dx.doi.org/10.3390/gels8040235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028337/
https://www.ncbi.nlm.nih.gov/pubmed/35448136
http://dx.doi.org/10.3390/gels8040235

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