HO-1 Upregulation by Kaempferol via ROS-Dependent Nrf2-ARE Cascade Attenuates Lipopolysaccharide-Mediated Intercellular Cell Adhesion Molecule-1 Expression in Human Pulmonary Alveolar Epithelial Cells

Lung inflammation is a pivotal event in the pathogenesis of acute lung injury. Heme oxygenase-1 (HO-1) is a key antioxidant enzyme that could be induced by kaempferol (KPR) and exerts anti-inflammatory effects. However, the molecular mechanisms of KPR-mediated HO-1 expression and its effects on infl...

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Detalles Bibliográficos
Autores principales: Yang, Chien-Chung, Hsiao, Li-Der, Wang, Chen-Yu, Lin, Wei-Ning, Shih, Ya-Fang, Chen, Yi-Wen, Cho, Rou-Ling, Tseng, Hui-Ching, Yang, Chuen-Mao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028455/
https://www.ncbi.nlm.nih.gov/pubmed/35453467
http://dx.doi.org/10.3390/antiox11040782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028455/
https://www.ncbi.nlm.nih.gov/pubmed/35453467
http://dx.doi.org/10.3390/antiox11040782

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