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Treatment of Painful Palmoplantar Keratoderma Related to Pachyonychia Congenita Using EGFR Inhibitors

Pachyonychia congenita (PC) is a genodermatosis associated with severe painful palmoplantar keratoderma (PPK) and thickened dystrophic nails caused by autosomal dominant-negative mutations in five genes encoding keratins 6A-B-C, 16, and 17. The mechanical, surgical, or medical options for painful PC...

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Detalles Bibliográficos
Autores principales: Greco, Céline, Ponsen, Anne-Charlotte, Leclerc-Mercier, Stéphanie, Schlatter, Joël, Cisternino, Salvatore, Boucheix, Claude, Bodemer, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028469/
https://www.ncbi.nlm.nih.gov/pubmed/35453591
http://dx.doi.org/10.3390/biomedicines10040841