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Increased Indoleamine 2,3-Dioxygenase 1 (IDO-1) Activity and Inflammatory Responses during Chikungunya Virus Infection

Chikungunya virus (CHIKV) infection causes intense cytokine/chemokine inflammatory responses and debilitating joint pain. Indoleamine2,3–dioxygenase 1 (IDO-1) is an enzyme that initiates the tryptophan degradation that is important in initial host innate immune defense against infectious pathogens....

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Detalles Bibliográficos
Autores principales: Alves de Souza, Thiara Manuele, Fernandes-Santos, Caroline, Araújo da Paixão de Oliveira, Jéssica, Tomé, Larissa Cristina Teixeira, Fiestas-Solórzano, Victor Edgar, Nunes, Priscila Conrado Guerra, Guimaraes, Gabriel Macedo Costa, Sánchez-Arcila, Juan Camilo, Paiva, Iury Amâncio, de Souza, Luís Jose, Damasco, Paulo Vieira, da Silva Frutuoso, Válber, Heringer, Manoela, de Oliveira-Pinto, Luzia Maria, Pinheiro, Roberta Olmo, dos Santos, Flavia Barreto, Leal de Azeredo, Elzinandes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028473/
https://www.ncbi.nlm.nih.gov/pubmed/35456119
http://dx.doi.org/10.3390/pathogens11040444