Advances in Thymidine Kinase 2 Deficiency: Clinical Aspects, Translational Progress, and Emerging Therapies

Defects in the replication, maintenance, and repair of mitochondrial DNA (mtDNA) constitute a growing and genetically heterogeneous group of mitochondrial disorders. Multiple genes participate in these processes, including thymidine kinase 2 (TK2) encoding the mitochondrial matrix protein TK2, a cri...

Descripción completa

Detalles Bibliográficos
Autores principales: Berardo, Andres, Domínguez-González, Cristina, Engelstad, Kristin, Hirano, Michio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028656/
https://www.ncbi.nlm.nih.gov/pubmed/35094997
http://dx.doi.org/10.3233/JND-210786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028656/
https://www.ncbi.nlm.nih.gov/pubmed/35094997
http://dx.doi.org/10.3233/JND-210786

Ejemplares similares