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Diminished LC3-Associated Phagocytosis by Huntington’s Disease Striatal Astrocytes

BACKGROUND: In recent years the functions of astrocytes have shifted from conventional supportive roles to also include active roles in altering synapses and engulfment of cellular debris. Recent studies have implicated astrocytes in both protective and pathogenic roles impacting Huntington’s diseas...

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Detalles Bibliográficos
Autores principales: Wakida, Nicole M., Lau, Alice L., Nguyen, Jessica, Cruz, Gladys Mae S., Fote, Gianna M., Steffan, Joan S., Thompson, Leslie M., Berns, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028675/
https://www.ncbi.nlm.nih.gov/pubmed/35253772
http://dx.doi.org/10.3233/JHD-210502