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Vaccine Can Induce CD4-Mediated Responses to Homocitrullinated Peptides via Multiple HLA-Types and Confer Anti-Tumor Immunity

Homocitrullination is the post translation modification (PTM) of the amino acid lysine to homocitrulline also referred to as carbamylation. This PTM has mainly been studied in relation to autoimmune diseases including rheumatoid arthritis. Homocitrullination of lysines alters their charge which can...

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Detalles Bibliográficos
Autores principales: Cook, Katherine, Xue, Wei, Atabani, Suha, Symonds, Peter, Al Omari, Abdullah, Daniels, Ian, Shah, Sabaria, Choudhury, Ruhul Hasan, Weston, Daisy, Metheringham, Rachael, Brentville, Victoria, Durrant, Lindy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028767/
https://www.ncbi.nlm.nih.gov/pubmed/35464453
http://dx.doi.org/10.3389/fimmu.2022.873947