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Expression of CD39 Identifies Activated Intratumoral CD8+ T Cells in Mismatch Repair Deficient Endometrial Cancer

SIMPLE SUMMARY: Identification of human cancer-reactive CD8+ T cells is crucial for the stratification of patients for immunotherapy and determination of immune-therapeutic effects. Here, we report on the CD103− CD39+ subset of CD8+ T cells in tumors and reveal this subset to be activated and likely...

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Detalles Bibliográficos
Autores principales: Lubbers, Joyce M., Ważyńska, Marta A., van Rooij, Nienke, Kol, Arjan, Workel, Hagma H., Plat, Annechien, Paijens, Sterre T., Vlaming, Martijn R., Spierings, Diana C. J., Elsinga, Philip H., Bremer, Edwin, Nijman, Hans W., de Bruyn, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028869/
https://www.ncbi.nlm.nih.gov/pubmed/35454831
http://dx.doi.org/10.3390/cancers14081924