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Expression of CD39 Identifies Activated Intratumoral CD8+ T Cells in Mismatch Repair Deficient Endometrial Cancer
SIMPLE SUMMARY: Identification of human cancer-reactive CD8+ T cells is crucial for the stratification of patients for immunotherapy and determination of immune-therapeutic effects. Here, we report on the CD103− CD39+ subset of CD8+ T cells in tumors and reveal this subset to be activated and likely...
Autores principales: | Lubbers, Joyce M., Ważyńska, Marta A., van Rooij, Nienke, Kol, Arjan, Workel, Hagma H., Plat, Annechien, Paijens, Sterre T., Vlaming, Martijn R., Spierings, Diana C. J., Elsinga, Philip H., Bremer, Edwin, Nijman, Hans W., de Bruyn, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028869/ https://www.ncbi.nlm.nih.gov/pubmed/35454831 http://dx.doi.org/10.3390/cancers14081924 |
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