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Mechanical Cues, E-Cadherin Expression and Cell “Sociality” Are Crucial Crossroads in Determining Pancreatic Ductal Adenocarcinoma Cells Behavior

E-cadherin, an epithelial-to-mesenchymal transition (EMT) marker, is coupled to actin cytoskeleton and distributes cell forces acting on cells. Since YAP transduces mechanical signals involving actin cytoskeleton, we aimed to investigate the relationship between YAP and mechanical cues in pancreatic...

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Detalles Bibliográficos
Autores principales: Bianchi, Francesca, Sommariva, Michele, Cornaghi, Laura Brigida, Denti, Luca, Nava, Ambra, Arnaboldi, Francesca, Moscheni, Claudia, Gagliano, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028873/
https://www.ncbi.nlm.nih.gov/pubmed/35455997
http://dx.doi.org/10.3390/cells11081318