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Role of Polyamines and Hypusine in β Cells and Diabetes Pathogenesis

The polyamines—putrescine, spermidine, and spermine—are polycationic, low molecular weight amines with cellular functions primarily related to mRNA translation and cell proliferation. Polyamines partly exert their effects via the hypusine pathway, wherein the polyamine spermidine provides the aminob...

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Detalles Bibliográficos
Autores principales: Kulkarni, Abhishek, Anderson, Cara M., Mirmira, Raghavendra G., Tersey, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028953/
https://www.ncbi.nlm.nih.gov/pubmed/35448531
http://dx.doi.org/10.3390/metabo12040344