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Role of Polyamines and Hypusine in β Cells and Diabetes Pathogenesis
The polyamines—putrescine, spermidine, and spermine—are polycationic, low molecular weight amines with cellular functions primarily related to mRNA translation and cell proliferation. Polyamines partly exert their effects via the hypusine pathway, wherein the polyamine spermidine provides the aminob...
Autores principales: | Kulkarni, Abhishek, Anderson, Cara M., Mirmira, Raghavendra G., Tersey, Sarah A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028953/ https://www.ncbi.nlm.nih.gov/pubmed/35448531 http://dx.doi.org/10.3390/metabo12040344 |
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