Pcsk6 Deficiency Promotes Cardiomyocyte Senescence by Modulating Ddit3-Mediated ER Stress

Cardiac aging is a critical determinant of cardiac dysfunction, which contributes to cardiovascular disease in the elderly. Proprotein convertase subtilisin/kexin 6 (PCSK6) is a proteolytic enzyme important for the maintenance of cardiac function and vascular homeostasis. To date, the involvement of...

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Detalles Bibliográficos
Autores principales: Zhan, Wenxing, Chen, Liping, Liu, Hongfei, Long, Changkun, Liu, Jiankun, Ding, Shuangjin, Wu, Qingyu, Chen, Shenghan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028967/
https://www.ncbi.nlm.nih.gov/pubmed/35456517
http://dx.doi.org/10.3390/genes13040711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028967/
https://www.ncbi.nlm.nih.gov/pubmed/35456517
http://dx.doi.org/10.3390/genes13040711

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