Population Pharmacokinetic (Pop-PK) Analysis of Torsemide in Healthy Korean Males Considering CYP2C9 and OATP1B1 Genetic Polymorphisms

Torsemide is a diuretic drug used for several cardiovascular and chronic diseases. With regard to the clinical application of torsemide, studies on individualized pharmacotherapy and modeling that take variability in pharmacokinetics (PKs) within a population into account have been rarely reported....

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Detalles Bibliográficos
Autores principales: Jeong, Seung-Hyun, Jang, Ji-Hun, Cho, Hea-Young, Lee, Yong-Bok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028991/
https://www.ncbi.nlm.nih.gov/pubmed/35456605
http://dx.doi.org/10.3390/pharmaceutics14040771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028991/
https://www.ncbi.nlm.nih.gov/pubmed/35456605
http://dx.doi.org/10.3390/pharmaceutics14040771

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