Cargando…
Population Pharmacokinetic (Pop-PK) Analysis of Torsemide in Healthy Korean Males Considering CYP2C9 and OATP1B1 Genetic Polymorphisms
Torsemide is a diuretic drug used for several cardiovascular and chronic diseases. With regard to the clinical application of torsemide, studies on individualized pharmacotherapy and modeling that take variability in pharmacokinetics (PKs) within a population into account have been rarely reported....
Autores principales: | Jeong, Seung-Hyun, Jang, Ji-Hun, Cho, Hea-Young, Lee, Yong-Bok |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028991/ https://www.ncbi.nlm.nih.gov/pubmed/35456605 http://dx.doi.org/10.3390/pharmaceutics14040771 |
Ejemplares similares
-
Torsemide Pharmacometrics in Healthy Adult Populations Including CYP2C9 Genetic Polymorphisms and Various Patient Groups through Physiologically Based Pharmacokinetic-Pharmacodynamic Modeling
por: Jeong, Seung-Hyun, et al.
Publicado: (2022) -
Population Pharmacokinetics of Cis-, Trans-, and Total Cefprozil in Healthy Male Koreans
por: Jang, Ji-Hun, et al.
Publicado: (2019) -
Pharmacokinetic and pharmacodynamic properties of orally administered torsemide in healthy horses
por: Agne, Gustavo F., et al.
Publicado: (2018) -
Influence of OATP1B1 and BCRP polymorphisms on the pharmacokinetics and pharmacodynamics of rosuvastatin in elderly and young Korean subjects
por: Kim, Yun, et al.
Publicado: (2019) -
Population Pharmacokinetic Analysis of Tiropramide in Healthy Korean Subjects
por: Jeong, Seung-Hyun, et al.
Publicado: (2020)