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The Effectiveness of Isoplumbagin and Plumbagin in Regulating Amplitude, Gating Kinetics, and Voltage-Dependent Hysteresis of erg-mediated K(+) Currents

Isoplumbagin (isoPLB, 5-hydroxy-3-methyl-1,4-naphthoquinone), a naturally occurring quinone, has been observed to exercise anti-inflammatory, antimicrobial, and antineoplastic activities. Notably, whether and how isoPLB, plumbagin (PLB), or other related compounds impact transmembrane ionic currents...

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Detalles Bibliográficos
Autores principales: Chen, Linyi, Cho, Hsin-Yen, Chuang, Tzu-Hsien, Ke, Ting-Ling, Wu, Sheng-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029050/
https://www.ncbi.nlm.nih.gov/pubmed/35453530
http://dx.doi.org/10.3390/biomedicines10040780