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Transcriptomics of Acute DENV-Specific CD8+ T Cells Does Not Support Qualitative Differences as Drivers of Disease Severity

While several lines of evidence suggest a protective role of T cells against disease associated with Dengue virus (DENV) infection, their potential contribution to immunopathology in the acute phase of DENV infection remains controversial, and it has been hypothesized that the more severe form of th...

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Detalles Bibliográficos
Autores principales: Grifoni, Alba, Voic, Hannah, Yu, Esther Dawen, Mateus, Jose, Yan Fung, Kai Mei, Wang, Alice, Seumois, Grégory, De Silva, Aruna D., Tennekon, Rashika, Premawansa, Sunil, Premawansa, Gayani, Tippalagama, Rashmi, Wijewickrama, Ananda, Chawla, Ashu, Greenbaum, Jason, Peters, Bjoern, Pandurangan, Vijayanand, Weiskopf, Daniela, Sette, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029181/
https://www.ncbi.nlm.nih.gov/pubmed/35455361
http://dx.doi.org/10.3390/vaccines10040612