Cargando…

Transcriptomics of Acute DENV-Specific CD8+ T Cells Does Not Support Qualitative Differences as Drivers of Disease Severity

While several lines of evidence suggest a protective role of T cells against disease associated with Dengue virus (DENV) infection, their potential contribution to immunopathology in the acute phase of DENV infection remains controversial, and it has been hypothesized that the more severe form of th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grifoni, Alba, Voic, Hannah, Yu, Esther Dawen, Mateus, Jose, Yan Fung, Kai Mei, Wang, Alice, Seumois, Grégory, De Silva, Aruna D., Tennekon, Rashika, Premawansa, Sunil, Premawansa, Gayani, Tippalagama, Rashmi, Wijewickrama, Ananda, Chawla, Ashu, Greenbaum, Jason, Peters, Bjoern, Pandurangan, Vijayanand, Weiskopf, Daniela, Sette, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029181/ https://www.ncbi.nlm.nih.gov/pubmed/35455361 http://dx.doi.org/10.3390/vaccines10040612

Ejemplares similares

A Population of CD4(+)CD8(+) Double-Positive T Cells Associated with Risk of Plasma Leakage in Dengue Viral Infection
por: Yu, Esther Dawen, et al.
Publicado: (2022)

Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA
por: Tian, Yuan, et al.
Publicado: (2017)

Molecular Signatures of Dengue Virus-Specific IL-10/IFN-γ Co-producing CD4 T Cells and Their Association with Dengue Disease
por: Tian, Yuan, et al.
Publicado: (2019)

Circulating T cell-monocyte complexes are markers of immune perturbations
por: Burel, Julie G, et al.
Publicado: (2019)

Characterization of Magnitude and Antigen Specificity of HLA-DP, DQ, and DRB3/4/5 Restricted DENV-Specific CD4+ T Cell Responses
por: Grifoni, Alba, et al.
Publicado: (2019)

Is Total Serum Nitrite and Nitrate (NOx) Level in Dengue Patients a Potential Prognostic Marker of Dengue Hemorrhagic Fever?
por: Mapalagamage, Maheshi, et al.
Publicado: (2018)

Predicting Cell Types and Genetic Variations Contributing to Disease by Combining GWAS and Epigenetic Data
por: Gerasimova, Anna, et al.
Publicado: (2013)

The Challenge of Distinguishing Cell–Cell Complexes from Singlet Cells in Non‐Imaging Flow Cytometry and Single‐Cell Sorting
por: Burel, Julie G., et al.
Publicado: (2020)

Identification of Novel Yellow Fever Class II Epitopes in YF-17D Vaccinees
por: Mateus, Jose, et al.
Publicado: (2020)

Predictive value of hepatic transaminases during febrile phase as a predictor of a severe form of Dengue: analysis of adult Dengue patients from a tertiary care setting of Sri Lanka
por: Priyangika, Dickowita Kankanamge Dilani, et al.
Publicado: (2021)

Positive melioidosis serology in a patient with adult onset Still’s disease: a case report of a diagnostic dilemma
por: Dissanayake, Harsha Anuruddhika, et al.
Publicado: (2018)

Post-streptococcal glomerulonephritis leading to posterior reversible encephalopathy syndrome: a case report
por: Adikari, Madura, et al.
Publicado: (2014)

Rare cardiac sequelae of a hump-nosed viper bite
por: Thillainathan, Sharmila, et al.
Publicado: (2015)

Imbalance of Regulatory and Cytotoxic SARS-CoV-2-Reactive CD4(+) T Cells in COVID-19
por: Meckiff, Benjamin J., et al.
Publicado: (2020)

17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells
por: Schmiedel, Benjamin Joachim, et al.
Publicado: (2016)

Single-cell profiling reveals distinct subsets of CD14+ monocytes drive blood immune signatures of active tuberculosis
por: Hillman, Hannah, et al.
Publicado: (2023)

A case report of co-infection of Melioidosis and cutaneous Leishmaniasis
por: Kahandawaarachchi, Isuru Chamika Indeewara, et al.
Publicado: (2017)

Diagnosis of Leptospirosis: Comparison between Microscopic Agglutination Test, IgM-ELISA and IgM Rapid Immunochromatography Test
por: Niloofa, Roshan, et al.
Publicado: (2015)

First Complete Cytochrome B Sequences and Molecular Taxonomy of Bat Species from Sri Lanka
por: Perera, Thejanee, et al.
Publicado: (2022)

Detection of Alpha- and Betacoronaviruses in Miniopterus fuliginosus and Rousettus leschenaultii, two species of Sri Lankan Bats
por: Muzeniek, Therese, et al.
Publicado: (2021)

Paramyxovirus Diversity within One Population of Miniopterus fuliginosus Bats in Sri Lanka
por: Muzeniek, Therese, et al.
Publicado: (2022)

Full Genome of batCoV/MinFul/2018/SriLanka, a Novel Alpha-Coronavirus Detected in Miniopterus fuliginosus, Sri Lanka
por: Muzeniek, Therese, et al.
Publicado: (2022)

Comparative virome analysis of individual shedding routes of Miniopterus phillipsi bats inhabiting the Wavul Galge cave, Sri Lanka
por: Muzeniek, Therese, et al.
Publicado: (2023)

Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure
por: Murray, Mallory Paynich, et al.
Publicado: (2021)

Quantitative and Qualitative Perturbations of CD8(+) MAITs in Healthy Mycobacterium tuberculosis–Infected Individuals
por: Pomaznoy, Mikhail, et al.
Publicado: (2020)

CD4+CCR6+ T cells dominate the BCG-induced transcriptional signature
por: Singhania, Akul, et al.
Publicado: (2021)

Immunological memory to Common Cold Coronaviruses assessed longitudinally over a three-year period
por: Yu, Esther Dawen, et al.
Publicado: (2022)

Immunological memory to common cold coronaviruses assessed longitudinally over a three-year period pre-COVID19 pandemic
por: Yu, Esther Dawen, et al.
Publicado: (2022)

Identifying Candidate Targets of Immune Responses in Zika Virus Based on Homology to Epitopes in Other Flavivirus Species
por: Xu, Xiaojun, et al.
Publicado: (2016)

SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19
por: Grifoni, Alba, et al.
Publicado: (2021)

SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19
por: Grifoni, Alba, et al.
Publicado: (2022)

Properties of MHC Class I Presented Peptides That Enhance Immunogenicity
por: Calis, Jorg J. A., et al.
Publicado: (2013)

Genetic risk for dengue hemorrhagic fever and dengue fever in multiple ancestries
por: Pare, Guillaume, et al.
Publicado: (2020)

Human T Cell Response to Dengue Virus Infection
por: Tian, Yuan, et al.
Publicado: (2019)

Balanced Cellular and Humoral Immune Responses Targeting Multiple Antigens in Adults Receiving a Quadrivalent Inactivated Influenza Vaccine
por: Yu, Esther Dawen, et al.
Publicado: (2021)

Extended-spectrum ß-Lactamase-producing Enterobacteriaceae as a Common Cause of Urinary Tract Infections in Sri Lanka
por: Tillekeratne, L. Gayani, et al.
Publicado: (2016)

Classical CD4 T cells as the cornerstone of antimycobacterial immunity
por: Morgan, Jeffrey, et al.
Publicado: (2021)

Polymorphisms of Transporter Associated with Antigen Presentation, Tumor Necrosis Factor-α and Interleukin-10 and their Implications for Protection and Susceptibility to Severe Forms of Dengue Fever in Patients in Sri Lanka
por: Fernando, Anira N, et al.
Publicado: (2015)

Development of a novel clustering tool for linear peptide sequences
por: Dhanda, Sandeep K., et al.
Publicado: (2018)

Pre-existing T Cell Memory against Zika Virus
por: Schouest, Blake, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_dlpbu337jil6b58sns6hd6197b