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Enhanced Cytotoxic Effects in Human Oral Squamous Cell Carcinoma Cells Treated with Combined Methyltransferase Inhibitors and Histone Deacetylase Inhibitors

Combined treatment of human oral squamous cell carcinoma (OSCCs) with DNA methyltransferase inhibitors (DNMTis), histone methyltransferase inhibitors (HMTis), and histone deacetylase inhibitors (HDACis), and the molecular mechanisms underlying their anticancer effects, have not been fully elucidated...

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Detalles Bibliográficos
Autores principales: Ushio, Ryosuke, Hiroi, Miki, Matsumoto, Ari, Mori, Kazumasa, Yamamoto, Nobuharu, Ohmori, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029187/
https://www.ncbi.nlm.nih.gov/pubmed/35453513
http://dx.doi.org/10.3390/biomedicines10040763