Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis

Hematopoiesis changes over life to meet the demands of maturation and aging. Here, we find that the definitive hematopoietic stem and progenitor cell (HSPC) compartment is remodeled from gestation into adulthood, a process regulated by the heterochronic Lin28b/let-7 axis. Native fetal and neonatal H...

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Detalles Bibliográficos
Autores principales: Wang, Dahai, Tanaka-Yano, Mayuri, Meader, Eleanor, Kinney, Melissa A., Morris, Vivian, Lummertz da Rocha, Edroaldo, Liu, Nan, Liu, Tianxin, Zhu, Qian, Orkin, Stuart H., North, Trista E., Daley, George Q., Rowe, R. Grant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029260/
https://www.ncbi.nlm.nih.gov/pubmed/35385744
http://dx.doi.org/10.1016/j.celrep.2022.110587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029260/
https://www.ncbi.nlm.nih.gov/pubmed/35385744
http://dx.doi.org/10.1016/j.celrep.2022.110587

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