Cargando…

BRD4 Targets the KEAP1-Nrf2-G6PD Axis and Suppresses Redox Metabolism in Small Cell Lung Cancer

Accumulating evidence has witnessed the Kelch-like ECH-associated protein 1(KEAP1)- nuclear factor (erythroid-derived 2)-like 2 (Nrf2) axis is the main regulatory factor of cell resistance to endogenous and exogenous oxidative assaults. However, there are few studies addressing the upstream regulato...

Descripción completa

Detalles Bibliográficos
Autores principales: Lv, Yang, Lv, Xiaotong, Zhang, Jiahui, Cao, Guozhen, Xu, Changzhi, Zhang, Buchang, Lin, Wenchu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029261/
https://www.ncbi.nlm.nih.gov/pubmed/35453346
http://dx.doi.org/10.3390/antiox11040661