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Hot Melt Extrusion-Triggered Amorphization as a Continuous Process for Inducing Extended Supersaturable Drug Immediate-Release from saSMSDs Systems

Hot melt extrusion (HME), a continuous manufacturing process for generating supersaturating amorphous self-micellizing solid dispersion systems (saSMSDs), holds promise for achieving amorphization of many pharmaceutical formulations. For saSMSDs generation, HME-triggered continuous processes offer a...

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Detalles Bibliográficos
Autores principales: Yu, Huan, Zhang, Yanfei, Ma, Yinghui, Zhang, Huifeng, Hao, Chengyi, Zhang, Yong, Li, Zhengqiang, Qi, Xianrong, Shi, Nianqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029276/
https://www.ncbi.nlm.nih.gov/pubmed/35456600
http://dx.doi.org/10.3390/pharmaceutics14040765