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Synthesis and biological evaluation of indazole derivatives as anti-cancer agents

Several FDA approved small molecule anti-cancer drugs contain indazole scaffolds. Here, we report the design, synthesis and biological evaluation of a series of indazole derivatives. In vitro antiproliferative activity screening showed that compound 2f had potent growth inhibitory activity against s...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Liu, Zhihao, Wu, Xiuli, Gan, Cailing, Su, Xingping, Liu, Hongyao, Que, Hanyun, Zhang, Qianyu, Xue, Qiang, Yue, Lin, Yu, Luoting, Ye, Tinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029309/
https://www.ncbi.nlm.nih.gov/pubmed/35481216
http://dx.doi.org/10.1039/d1ra01147b