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Design, synthesis and evaluation of novel indole-2-carboxamides for growth inhibition of Mycobacterium tuberculosis and paediatric brain tumour cells

The omnipresent threat of tuberculosis (TB) and the scant treatment options thereof necessitate the development of new antitubercular agents, preferably working via a novel mechanism of action distinct from the current drugs. Various studies identified the mycobacterial membrane protein large 3 tran...

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Detalles Bibliográficos
Autores principales: Alsayed, Shahinda S. R., Lun, Shichun, Bailey, Anders W., Suri, Amreena, Huang, Chiang-Ching, Mocerino, Mauro, Payne, Alan, Sredni, Simone Treiger, Bishai, William R., Gunosewoyo, Hendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029315/
https://www.ncbi.nlm.nih.gov/pubmed/35481189
http://dx.doi.org/10.1039/d0ra10728j