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In Silico Identification of Novel Inhibitors Targeting the Homodimeric Interface of Superoxide Dismutase from the Dental Pathogen Streptococcus mutans

The microaerophile Streptococcus mutans, the main microaerophile responsible for the development of dental plaque, has a single cambialistic superoxide dismutase (SmSOD) for its protection against reactive oxygen species. In order to discover novel inhibitors of SmSOD, possibly interfering with the...

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Detalles Bibliográficos
Autores principales: Cerchia, Carmen, Roscetto, Emanuela, Nasso, Rosarita, Catania, Maria Rosaria, De Vendittis, Emmanuele, Lavecchia, Antonio, Masullo, Mariorosario, Rullo, Rosario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029323/
https://www.ncbi.nlm.nih.gov/pubmed/35453470
http://dx.doi.org/10.3390/antiox11040785