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In Vivo Investigation of (2-Hydroxypropyl)-β-cyclodextrin-Based Formulation of Spironolactone in Aqueous Solution for Paediatric Use

Spironolactone (SPL), a potent anti-aldosterone steroidal drug used to treat several diseases in paediatric patients (e.g., hypertension, primary aldosteronism, Bartter’s syndrome, and congestive heart failure), is not available in child-friendly dosage forms, and spironolactone liquids have been re...

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Detalles Bibliográficos
Autores principales: Lopalco, Antonio, Manni, Annachiara, Keeley, Alexander, Haider, Shozeb, Li, Wenliang, Lopedota, Angela, Altomare, Cosimo Damiano, Denora, Nunzio, Tuleu, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029429/
https://www.ncbi.nlm.nih.gov/pubmed/35456614
http://dx.doi.org/10.3390/pharmaceutics14040780