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In Vivo Investigation of (2-Hydroxypropyl)-β-cyclodextrin-Based Formulation of Spironolactone in Aqueous Solution for Paediatric Use
Spironolactone (SPL), a potent anti-aldosterone steroidal drug used to treat several diseases in paediatric patients (e.g., hypertension, primary aldosteronism, Bartter’s syndrome, and congestive heart failure), is not available in child-friendly dosage forms, and spironolactone liquids have been re...
Autores principales: | Lopalco, Antonio, Manni, Annachiara, Keeley, Alexander, Haider, Shozeb, Li, Wenliang, Lopedota, Angela, Altomare, Cosimo Damiano, Denora, Nunzio, Tuleu, Catherine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029429/ https://www.ncbi.nlm.nih.gov/pubmed/35456614 http://dx.doi.org/10.3390/pharmaceutics14040780 |
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