Replicative Stress Coincides with Impaired Nuclear DNA Damage Response in COX4-1 Deficiency

Cytochrome c oxidase (COX), a multimeric protein complex, is the final electron acceptor in the mitochondrial electron transfer chain. Primary COX deficiency, caused by mutations in either mitochondrial DNA or nuclear-encoded genes, is a heterogenous group of mitochondrial diseases with a wide range...

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Detalles Bibliográficos
Autores principales: Douiev, Liza, Miller, Chaya, Keller, Guy, Benyamini, Hadar, Abu-Libdeh, Bassam, Saada, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029573/
https://www.ncbi.nlm.nih.gov/pubmed/35456968
http://dx.doi.org/10.3390/ijms23084149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029573/
https://www.ncbi.nlm.nih.gov/pubmed/35456968
http://dx.doi.org/10.3390/ijms23084149

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