Effects of Anticancer Agent P-bi-TAT on Gene Expression Link the Integrin Thyroid Hormone Receptor to Expression of Stemness and Energy Metabolism Genes in Cancer Cells

Chemically modified forms of tetraiodothyroacetic acid (tetrac), an L-thyroxine derivative, have been shown to exert their anticancer activity at plasma membrane integrin αvβ3 of tumor cells. Via a specific hormone receptor on the integrin, tetrac-based therapeutic agents modulate expression of gene...

Descripción completa

Detalles Bibliográficos
Autores principales: Glinsky, Gennadi V., Godugu, Kavitha, Sudha, Thangirala, Rajabi, Mehdi, Chittur, Sridar V., Hercbergs, Aleck A., Mousa, Shaker A., Davis, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029602/
https://www.ncbi.nlm.nih.gov/pubmed/35448512
http://dx.doi.org/10.3390/metabo12040325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029602/
https://www.ncbi.nlm.nih.gov/pubmed/35448512
http://dx.doi.org/10.3390/metabo12040325

Ejemplares similares