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Effects of Anticancer Agent P-bi-TAT on Gene Expression Link the Integrin Thyroid Hormone Receptor to Expression of Stemness and Energy Metabolism Genes in Cancer Cells

Chemically modified forms of tetraiodothyroacetic acid (tetrac), an L-thyroxine derivative, have been shown to exert their anticancer activity at plasma membrane integrin αvβ3 of tumor cells. Via a specific hormone receptor on the integrin, tetrac-based therapeutic agents modulate expression of gene...

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Detalles Bibliográficos
Autores principales:	Glinsky, Gennadi V., Godugu, Kavitha, Sudha, Thangirala, Rajabi, Mehdi, Chittur, Sridar V., Hercbergs, Aleck A., Mousa, Shaker A., Davis, Paul J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029602/ https://www.ncbi.nlm.nih.gov/pubmed/35448512 http://dx.doi.org/10.3390/metabo12040325

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